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Volume 11(1); January 2022

Original Articles
[English]

Food thickeners are commonly used to prepare thickened liquids for the management of dysphagia. The National Dysphagia Diet (NDD) thickness levels of thickened liquids prepared with commercial food thickeners are known to vary depending on the thickener type, recommended amount of thickener, thickener brand, and preparation instructions. Particularly, detailed preparation instructions must be provided by the manufacturers to achieve the correct thickness levels. However, the rheological information on product labels provided by manufacturers is typically not accurate. Here, various pudding-thick liquids were prepared by mixing commercial xanthan gum (XG)-based thickeners based on the manufacturers’ guidelines, and their rheological properties were characterized. Several thickened liquids prepared with four different XG-based thickeners (A-D) marketed in Korea did not meet the pudding-like criterion (> 1,750 mPa·s) based on the NDD guidelines. Significant differences in rheological parameter values (ηa,50, n, and G′) were also identified among the various thickened liquids. Only one thickener (thickener A) manufactured in Korea showed optimal results, which satisfied the pudding-thick viscosity range for various food liquids and also showed lower stickiness and enhanced bolus formation ability for easy and safe swallowing when compared to other thickeners (B, C, and D).

Citations

Citations to this article as recorded by  
  • Difference in Drinking Times as a Function of Liquid Consistency in Adults With Oculopharyngeal Muscular Dystrophy: A Comparative Study Using Bostwick Consistometer and IDDSI Flow Test Methods
    Annie Villeneuve‐Rhéaume, Cynthia Gagnon, Isabelle Germain, Claudia Côté
    Journal of Texture Studies.2024;[Epub]     CrossRef
  • Effect of Thickened Beverage and Swallowing Aid Jelly Used for Dysphagic Patients on the Disintegration of Orally Administered Tablets
    Won Hyeong Cho, Whachun Yoo, Byoungseung Yoo
    Clinical Nutrition Research.2024; 13(2): 89.     CrossRef
  • In-Depth Analysıs of Exercıse and Impact to Basketball Athlete Performance from A Bıblıometrıc Perspectıve
    Davi SOFYAN, Khairul Hafezad ABDULLAH, Waleed A. HAMMOOD, Yusuf HİDAYAT
    Akdeniz Spor Bilimleri Dergisi.2022; 5(4): 785.     CrossRef
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[English]
The Status of Enteral Nutrition Formula Use by Dietitians in Hospitals Within Busan and Gyeongnam Area
Haejin Kang, Minji Woo, Eunju Park, Yoo Kyoung Park
Clin Nutr Res 2022;11(1):9-19.   Published online January 20, 2022
DOI: https://doi.org/10.7762/cnr.2022.11.1.9

This study was conducted to analyze the status of medical food selection process in hospitals within Busan and Gyeongnam area. The survey was distributed to 396 hospitals (general, tertiary and long-term care hospitals) and finally 68 surveys were used for analysis. The questionnaire consisted of 9 general items and 10 items related to enteral nutrition (EN). From the survey we found out that general hospitals and tertiary hospitals normally hire clinical dietitian, while long-term care hospitals hire dietitians with no further qualifications (χ2 = 27.918, p < 0.001). A significant relationship was found between hospital size and the priority for choosing medical foods for patients (χ2 = 11.852, p < 0.05). In general and tertiary hospitals, medical foods were provided exactly according to the doctor's prescription, whereas in long-term care hospitals, only half followed the doctor’s direction and half of them provided the products that has been conventionally used. There was also a significant relationship between hospital size and the method for determination of nutrition requirements (χ2 = 20.496, p < 0.001). Finally, the priority of considerations when developing a ‘medical food guidelines’ was shown in the following order; 1) the type of medical food that can be selected according to the disease state, 2) the nutrient content and comparison table for commercial products, and 3) how to manage complications that may occur when supplying medical food for patients. Developing an EN practice guideline for making a sensible selection of medical foods will provide a valuable information for better patient care.

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[English]
Study on the Improvement of Health and Nutrition Status After a 12-week Protein-Rich Supplementation Regimen in Children and Adolescents With Brain Lesions Disorder
Hyeji Yoon, Hyoung su Park, Xiangxue An, Seok Jun Park, Gwang Woong Go, Hyunjung Kim, Hyesoon Lee, Mee Na Kim, Yoo Kyoung Park
Clin Nutr Res 2022;11(1):20-31.   Published online January 31, 2022
DOI: https://doi.org/10.7762/cnr.2022.11.1.20

Through a survey on dietary intake of children and adolescents with brain lesions, the present study aimed to analyze the current status of nutrient intake and examine the effect of high-protein nutrient drink on their nutritional and muscle statuses. The study participants were 90 juvenile participants aged 8–19 years, with brain lesions. The participants were provided with a protein nutrient drink for 12 weeks and a questionnaire survey on dietary intake was performed to analyze the level of nutrient intake before and after ingestion. The physical measurements were taken to determine the improvements in nutrient and muscle statuses. The results showed that, before the intake of protein nutrient drink as a supplement, the participants exhibited lower height, weight, and body mass index than those of the standard levels of healthy individuals, and the level of nutrient intake through diet was lower than those of the required and recommended levels of nutrient intake for Koreans. Conversely, after the intake of protein nutrient drink for 12 weeks, the level of nutrient intake and physical statuses such as weight showed significant improvements. In addition, the muscle status had undergone approximately 10% of change during the intervention with no significant difference. Thus, to ensure an adequate level of nutrient supply to children and adolescents with brain lesions, there is an urgent need to develop a guideline of nutrient intake. The findings in this study are expected to serve as the basic data for such guidelines.

Citations

Citations to this article as recorded by  
  • The use of protein supplements in children with cerebral palsy: A scoping literature review
    Ineke Verreydt, Els Ortibus, Anja Van Campenhout, Kaat Desloovere, Daisy Rymen, Andrea Martinuzzi
    PLOS One.2025; 20(5): e0322730.     CrossRef
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[English]
Risk of Osteoporotic Fractures Among Obese Women Based on Body Mass Index and Waist Circumference: A Nationwide Cohort in South Korea
Gyeongsil Lee, Seulggie Choi, Yoosun Cho, Sang Min Park
Clin Nutr Res 2022;11(1):32-41.   Published online February 7, 2022
DOI: https://doi.org/10.7762/cnr.2022.11.1.32

We evaluated the association between obesity status by body mass index (BMI) or waist circumference (WC) and osteoporotic fracture risk. We collected data of 143,673 women with a mean age of 58.5 years without history of osteoporotic fracture from the Korean National Health Insurance Service Cohort. Participants were divided into four groups according to obesity by BMI and WC, normal BMI/WC (BMI 18.5–24.9 kg/m2 and WC < 85 cm, reference), obese BMI/normal WC (BMI ≥ 25 kg/m2 and WC < 85 cm), normal BMI/obese WC (BMI < 25 kg/m2 and WC ≥ 85 cm), and obese BMI/WC (BMI ≥ 25 kg/m2 and WC < 85cm). Cox proportional hazards regression analyses were performed to obtain hazard ratios (HRs) with 95% confidence intervals (CIs) for the subsequent median 6.0 years, which were adjusted for age, socioeconomic status, lifestyle, morbidity index, and osteoporosis medication. Compared with the normal group, normal BMI/obese WC was associated with a higher osteoporotic fracture risk after multivariable adjustment (HRs [95% CI], 1.13 [1.05–1.21]), and obese BMI/normal WC was associated with a lower osteoporotic fracture risk (0.89 [0.84–0.94]). Obese BMI/normal WC was associated with a lower risk for hip fractures (0.75 [0.57–0.99]). Obese BMI/normal WC was associated with decreased risk of osteoporotic fracture, whereas normal BMI/obese WC was associated with increased risk of osteoporotic fracture compared with the normal group among East Asian women in their late 40s or more.

Citations

Citations to this article as recorded by  
  • The beneficial effects of a probiotic mix on bone and lean mass are dependent on the diet in female mice
    Claes Ohlsson, Lina Lawenius, Yiwen Jiang, Karin Horkeby, Jianyao Wu, Karin H. Nilsson, Antti Koskela, Juha Tuukkanen, Sofia Movérare-Skrtic, Petra Henning, Klara Sjögren
    Scientific Reports.2025;[Epub]     CrossRef
  • Association between antibiotics use and osteoporotic fracture risk: a nationally representative retrospective cohort study
    Ji Won Lee, Sun Jae Park, Young Jun Park, Seogsong Jeong, Jihun Song, Hye Jun Kim, Jooyoung Chang, Kyae Hyung Kim, Ji Soo Kim, Yun Hwan Oh, Yoosun Cho, Sang Min Park
    Archives of Osteoporosis.2024;[Epub]     CrossRef
  • Trunk-to-leg-volume ratio is not associated with bone density or fracture risk in middle-aged adults: results from the National Health and Nutrition Examination Survey
    Brian K. Ferguson, Patrick B. Wilson
    Archives of Osteoporosis.2023;[Epub]     CrossRef
  • Added value of waist circumference to body mass index for predicting fracture risk in obesity: a prospective study from the CARTaGENE cohort
    Anne-Frédérique Turcotte, Sonia Jean, Suzanne N. Morin, Fabrice Mac-Way, Claudia Gagnon
    Archives of Osteoporosis.2023;[Epub]     CrossRef
  • Letter to the Editor From Zhou: “Blood Pressure Variability and the Risk of Fracture: A Nationwide Cohort Study”
    Qingju Zhou
    The Journal of Clinical Endocrinology & Metabolism.2022; 107(7): e3088.     CrossRef
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[English]
Red and Processed Meat Intake in Relation to Non-Alcoholic Fatty Liver Disease Risk: Results from a Case-Control Study
Fatemeh Rahimi-Sakak, Mahsa Maroofi, Hadi Emamat, Azita Hekmatdoost
Clin Nutr Res 2022;11(1):42-49.   Published online January 26, 2022
DOI: https://doi.org/10.7762/cnr.2022.11.1.42

Data on the association between dietary red meat intake and non-alcoholic fatty liver disease (NAFLD) are limited. We designed this case-control study to determine the association between red and processed meat consumption and risk of NAFLD in Iranian adults. A total of 999 eligible subjects, including 196 NAFLD patients and 803 non-NAFLD controls were recruited from hepatology clinics in Tehran, Iran. A reliable and validated food frequency questionnaire was used to evaluate the red and processed meat intakes. The analyzes performed showed that in an age- and gender-adjusted model, patients with the highest quartile of red meat intake had an approximately three-fold higher risk of NAFLD than those with the lowest quartile of intake (odds ratio [OR], 3.42; 95% confidence interval [CI], 2.16–5.43; p value < 0.001). Moreover, patients in the highest quartile of processed meat intake had a 3.28 times higher risk of NAFLD, compared to the lowest quartile(OR, 3.28; 95% CI, 1.97–5.46; p value < 0.001).Both these associations remained significant by implementing additional adjustments for body mass index, energy intake, dietary factors, diabetes, smoking, and physical activity (OR, 3.65; 95% CI, 1.85–7.18; p value < 0.001 and OR, 3.25; 95% CI, 1.57–6.73; p value = 0.002, respectively).Our findings indicate that both red and processed meat intakes are related to the increased odds of NAFLD; however, prospective studies are needed to confirm these results.

Citations

Citations to this article as recorded by  
  • Interrelationship between alcohol consumption, overnutrition, and pharmacotherapy for liver steatosis: Considerations and proposals
    Rodrigo Valenzuela, Camila Farías, Yasna Muñoz, Jessica Zúñiga-Hernández, Luis A. Videla
    Molecular and Cellular Endocrinology.2026; 611: 112676.     CrossRef
  • Associations between Ultra-processed Foods and Risk of Non-alcoholic Fatty Liver Disease in Patients with Type 2 Diabetes: A Cross-sectional Study
    A Alikhani, A Seraj, M.H Kakoienejad, H Poustchi, Z Yari
    Journal of Nutrition Sciences and Food Technology.2025; 20(1): 13.     CrossRef
  • Edible mushrooms as meat analogues: A comprehensive review of nutritional, therapeutic, and market potential
    Sibo Boro, Vivek Kambhampati, Sandeep Das, Deepanka Saikia
    Food Research International.2025; 214: 116632.     CrossRef
  • Association Between Meat Intake and Metabolic Dysfunction‐Associated Steatotic Liver Disease Incidence in a Korean Population From the Health Examinees Study
    Uyangamaa Nyamsuren, Yuan Peng, Sangah Shin
    Molecular Nutrition & Food Research.2025;[Epub]     CrossRef
  • Ultra-processed foods and non-alcoholic fatty liver disease: an updated systematic review and dose–response meta-analysis
    Jinghong Zhang, Long Shu, Xiaopei Chen
    Frontiers in Nutrition.2025;[Epub]     CrossRef
  • The cross–sectional association between ultra-processed food intake and metabolic dysfunction-associated steatotic liver disease
    Natalie Sun, Brenton Prescott, Jiantao Ma, Vanessa Xanthakis, Paula A. Quatromoni, Michelle T. Long, Maura E. Walker
    Clinical Nutrition ESPEN.2025; 66: 215.     CrossRef
  • Role of gut microbiota in the development of metabolic dysfunction-associated steatotic liver disease in inflammatory bowel disease
    Aneta Sokal-Dembowska, Kübra Ergan, Sara Jarmakiewicz-Czaja
    World Journal of Gastroenterology.2025;[Epub]     CrossRef
  • The Protective Effect of FOXO3 rs2802292 G-Allele on Food Intake in a Southern Italian Cohort Affected by MASLD
    Rossella Donghia, Elisabetta Di Nicola, Rossella Tatoli, Giovanna Forte, Martina Lepore Signorile, Caterina Bonfiglio, Marialaura Latrofa, Katia De Marco, Andrea Manghisi, Vittoria Disciglio, Candida Fasano, Paola Sanese, Filomena Cariola, Antonia Lucia B
    Nutrients.2025; 17(8): 1315.     CrossRef
  • Ultra-Processed Foods and Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): What Is the Evidence So Far?
    Eleni V. Geladari, Dimitris Kounatidis, Gerasimos Socrates Christodoulatos, Sotiria Psallida, Argyro Pavlou, Charalampia V. Geladari, Vassilios Sevastianos, Maria Dalamaga, Natalia G. Vallianou
    Nutrients.2025; 17(13): 2098.     CrossRef
  • Ultra‐Processed Food Intake and Risk of Adverse Liver Outcomes: A Meta‐Analysis
    Chang Guo, Wu‐cai Yang, Jie Zhou, Jian‐Jun Wang, Dong Ji
    Journal of Food Science.2025;[Epub]     CrossRef
  • The association between dietary consumption of amino acids and the risk of non-alcoholic fatty liver disease: a case-control study
    Asieh Mansour, Mohammad Abdollahi, Maryam Mirahmad, Soudabe Motamed, Atie Sadat Khorasanian, Seyed Hossein Mirlohi, Hossein Poustchi, Elaheh Amini, Farnaz Tavakoli, Mohammad Reza Mohajeri-Tehrani, Sayed Mahmoud Sajjadi-Jazi, Azita Hekmatdoost
    Nutrition & Metabolism.2025;[Epub]     CrossRef
  • Diet quality indices and odds of metabolic dysfunction-associated fatty liver disease: a case-control study
    Pushpamala Ramaiah, Kamilya Jamel Baljon, Sana A. Alsulami, Grace M. Lindsay, Lathamangeswari Chinnasamy
    Frontiers in Nutrition.2024;[Epub]     CrossRef
  • Association between processed and unprocessed red meat consumption and risk of nonalcoholic fatty liver disease: A systematic review and dose-response meta-analysis
    Qin Zhou, Huaidong Hu, Lina Hu, Shuaibin Liu, Jin Chen, Shiwen Tong
    Journal of Global Health.2024;[Epub]     CrossRef
  • Association of ultra-processed food intake with severe non-alcoholic fatty liver disease: a prospective study of 143073 UK Biobank participants
    Yi-Feng Zhang, Wanning Qiao, Jinhong Zhuang, Hanxiao Feng, Zhilan Zhang, Yang Zhang
    The Journal of nutrition, health and aging.2024; 28(10): 100352.     CrossRef
  • Red meat intake, faecal microbiome, serum trimethylamine N‐oxide and hepatic steatosis among Chinese adults
    Yong Huang, Jiawei Zhang, Yaozong Zhang, Wuqi Wang, Meiling Li, Bo Chen, Xiaoyu Zhang, Zhuang Zhang, Jiaqi Huang, Yong Jin, Hua Wang, Xuehong Zhang, Shi Yin, Wanshui Yang
    Liver International.2024; 44(5): 1142.     CrossRef
  • Adding a Leafy Vegetable Fraction to Diets Decreases the Risk of Red Meat Mortality in MASLD Subjects: Results from the MICOL Cohort
    Rossella Donghia, Rossella Tatoli, Angelo Campanella, Francesco Cuccaro, Caterina Bonfiglio, Gianluigi Giannelli
    Nutrients.2024; 16(8): 1207.     CrossRef
  • Ultra-Processed Food Intake Is Associated with Non-Alcoholic Fatty Liver Disease in Adults: A Systematic Review and Meta-Analysis
    Alex E. Henney, Conor S. Gillespie, Uazman Alam, Theresa J. Hydes, Daniel J. Cuthbertson
    Nutrients.2023; 15(10): 2266.     CrossRef
  • Dietary Patterns, Foods, and Nutrients to Ameliorate Non-Alcoholic Fatty Liver Disease: A Scoping Review
    Sofía Montemayor, Silvia García, Margalida Monserrat-Mesquida, Josep A. Tur, Cristina Bouzas
    Nutrients.2023; 15(18): 3987.     CrossRef
  • A review of experimental and clinical studies on the therapeutic effects of pomegranate (Punica granatum) on non‐alcoholic fatty liver disease: Focus on oxidative stress and inflammation
    Mohammad Yassin Zamanian, Mehraveh Sadeghi Ivraghi, Lusine G. Khachatryan, Diana E. Vadiyan, Hanie Yavarpour Bali, Maryam Golmohammadi
    Food Science & Nutrition.2023; 11(12): 7485.     CrossRef
  • Age-Related Dietary Habits and Blood Biochemical Parameters in Patients with and without Steatosis—MICOL Cohort
    Rossella Donghia, Pasqua Letizia Pesole, Antonino Castellaneta, Sergio Coletta, Francesco Squeo, Caterina Bonfiglio, Giovanni De Pergola, Roberta Rinaldi, Sara De Nucci, Gianluigi Giannelli, Alfredo Di Leo, Rossella Tatoli
    Nutrients.2023; 15(18): 4058.     CrossRef
  • Prevalence of non-alcoholic fatty liver and its related factors in Iran: Systematic review and meta-analysis
    Maryam Chegeni, Sairan Nili, Mehdi Darabi, Elham Gheysvandi, Razieh Zahedi, Elham Sharifian, Hamid Reza Shoraka, Mohammad Rostamkhani, Leili Abedi Gheshlaghi
    Journal of Education and Health Promotion.2023;[Epub]     CrossRef
  • Diet and Risk of Non-Alcoholic Fatty Liver Disease, Cirrhosis, and Liver Cancer: A Large Prospective Cohort Study in UK Biobank
    Wen Guo, Xinyuan Ge, Jing Lu, Xin Xu, Jiaxin Gao, Quanrongzi Wang, Ci Song, Qun Zhang, Chengxiao Yu
    Nutrients.2022; 14(24): 5335.     CrossRef
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[English]
The Association Between Low Carbohydrate Diet and Resting Metabolic Rate in Overweight and Obese Women: A Cross-Sectional Study
Seyedeh Forough Sajjadi, Atieh Mirzababaei, Sara Pooyan, Niloufar Rasaei, Mir-Saeed Yekaninejad, Farideh Shiraseb, Khadijeh Mirzaei
Clin Nutr Res 2022;11(1):50-61.   Published online January 31, 2022
DOI: https://doi.org/10.7762/cnr.2022.11.1.50

Resting metabolic rate (RMR) accounts for most daily energy expenditure. The low carbohydrate diet (LCD) attenuates decreases in RMR. This study aims to investigate the relationship between an LCD and RMR status among overweight and obese women. We enrolled 291 overweight and obese women in this cross-sectional study. Body mass index (BMI), fat mass, fat-free mass, visceral fat, and insulin level were assessed. RMR was measured using indirect calorimetry. LCD score (LCDS) was measured using a validated semi-quantitative food frequency questionnaire. Analysis of variance, independent sample t-test, and Multinomial logistic regression tests were used. Results showed no relationship between LCDS and deviation of normal RMR (DNR) even after adjust for confounders (increased [Inc.] RMR: odds ratio [OR], 0.97; 95% confidence interval [CI], 0.92–1.01; p = 0.20; decreased [Dec.] RMR: OR, 0.97; 95% CI, 0.94–1.00; p = 0.14). Some components of LCDS had no significant association with DNR, such as carbohydrate and Dec. RMR in adjusted model (OR, 1.62; 95% CI, 0.98–1.37; p = 0.08) and monounsaturated fatty acids and Dec. RMR in adjusted model (OR, 0.48; 95% CI, 0.21–1.10, p = 0.08). However, refined grains had a significant association with Inc. RMR in crude model (OR, 0.87; 95% CI, 0.77–0.99, p = 0.04). There is no association between LCDS and RMR status.

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[English]
Health-Related Quality of Life and Nutritional Status Are Related to Dietary Magnesium Intake in Chronic Obstructive Pulmonary Disease: A Cross-Sectional Study
Afsane Ahmadi, Mohammad Hassan Eftekhari, Zohreh Mazloom, Masoom Masoompour, Mohammad Fararooei, Morteza Zare, Najmeh Hejazi
Clin Nutr Res 2022;11(1):62-73.   Published online January 31, 2022
DOI: https://doi.org/10.7762/cnr.2022.11.1.62

An insufficient intake of magnesium may be associated with the development of chronic obstructive pulmonary disease (COPD). We aimed to determine the relationship between health related quality of life (QoL), anthropometric indices and nutritional status with dietary magnesium intake in COPD patients. Sixty-one COPD patients participated in this cross-sectional study. QoL and nutritional status were assessed. Furthermore, body composition, calf circumference, and muscle strength were measured; equations were used to calculate fat-free mass index, body mass index, and muscle mass value. Dietary magnesium intake was assessed by three 24-hours recalls and magnesium intake was categorized as ≤ 188.08 mg/day (A group) and > 188.08 mg/day (B group). The χ2, independent-sample t-test and Mann-Whitney test were used for statistical analysis. The p values less than 0.05 were considered significant. Of QoL assessments the total and impact mean scores of St. George's respiratory questionnaire in the B group were significantly lower than the means of the A group (p value = 0.007 and 0.005, respectively). The instrumental activity of daily living score was significantly improved in patients with higher consumption of dietary magnesium (p = 0.02). Participants had a significantly lower mean score of patient-generated subjective global assessment in the B group compared to the A group (p = 0.003). Higher intake of dietary magnesium can lead to improve QoL and nutrition status.

Citations

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  • The Association Between Dietary Magnesium Intake with Chronic Obstructive Pulmonary Disease and Lung Function in US Population: a Cross-sectional Study
    Zhi-Feng Lin, Hua-Wei Lin, Wan-Zhe Liao, Ze-Min Huang, Xiao-Yue Liao, Yi-Yao Wang, Xu-Guang Guo
    Biological Trace Element Research.2024; 202(7): 3062.     CrossRef
  • Herbal Sources of Magnesium as a Promising Multifaceted Intervention for the Management of COVID-19
    Mohammed Namiq Amin, Saba Rahimi Bahoosh, Mahdieh Eftekhari, Leila Hosseinzadeh
    Natural Product Communications.2022;[Epub]     CrossRef
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