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Volume 10(2); April 2021

Review Article

[English]
A New Paradigm for Clinical Nutrition Services in the Era of the Fourth Industrial Revolution
Ga Young Kim, Jung-Sook Seo
Clin Nutr Res 2021;10(2):95-106.   Published online April 19, 2021
DOI: https://doi.org/10.7762/cnr.2021.10.2.95

The role of clinical nutrition services is emphasized in the care of chronic diseases; the prevalence of chronic diseases continues to increase due to the living environment change, westernized dietary life and the aging population in Korea. The effectiveness of clinical nutrition services in the treatment of diseases in inpatients has been demonstrated in several studies. However, in recent days, innovative changes are pursued in clinical nutrition services through a convergence with information and communication technology (ICT), a core technology of the fourth industrial revolution such as big data, deep learning, and artificial intelligence (AI). The health care environment is changing from a medical treatment-oriented service to a preventive and personalized paradigm. Furthermore, we live in an era of personalization where we can personalize dietary aspects including food choice, cooking recipes, and nutrition in daily life. In addition, ICT technology can build a personalized nutrition platform in consideration of individual patient's diseases, genetic trait, and environment, all of which can be technical means in personalized nutrition management services. Personalized nutrition based on ICT technology is able to provide more standardized and high-quality clinical nutrition services to the patients. The purpose of this review is to examine the core technologies of the fourth industrial revolution affecting clinical nutrition services, and ultimately discuss how clinical nutrition professional should respond to ICT technology-related fields in the era of the new technological innovations.

Citations

Citations to this article as recorded by  
  • Multi-indicator analytical study of 18 trace elements and fat in 5 beans based on entropy analysis (EA) and gray pattern recognition (GPR)
    Libing Zhou, Shoufang Hou
    International Journal of Food Properties.2024; 27(1): 616.     CrossRef
  • Omics biomarkers and an approach for their practical implementation to delineate health status for personalized nutrition strategies
    Jaap Keijer, Xavier Escoté, Sebastià Galmés, Andreu Palou-March, Francisca Serra, Mona Adnan Aldubayan, Kristina Pigsborg, Faidon Magkos, Ella J. Baker, Philip C. Calder, Joanna Góralska, Urszula Razny, Malgorzata Malczewska-Malec, David Suñol, Mar Galofr
    Critical Reviews in Food Science and Nutrition.2024; 64(23): 8279.     CrossRef
  • Implementation of a Case Presentation Program for Clinical Nutrition Students
    Shaahin Shahbazi, Maryam Vahdat Shariatpanahi, Saba Vahdatshariatpanahi, Erfan Shahbazi, Zahra Vahdat Shariatpanahi
    Frontiers in Nutrition.2022;[Epub]     CrossRef
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Original Articles

[English]
Target Calorie Intake Achievements for Patients Treated in the Surgical Intensive Care Unit
Min Kyoon Kim, Yoo Shin Choi, Suk Won Suh, Seung Eun Lee, Yong Gum Park, Hyun Kang
Clin Nutr Res 2021;10(2):107-114.   Published online April 19, 2021
DOI: https://doi.org/10.7762/cnr.2021.10.2.107

Adequate nutritional support in critically ill patients is important, however, sometimes it has been neglected in perioperative period of patients at surgical intensive care units (SICU). The aim of this study was to investigate whether approaching target calorie intake of surgical patients influences on their clinical outcomes. A total of 279 patients who admitted at SICU in perioperative period from August 2014 to July 2016 at our hospital were analyzed. Demographics, supplied calorie amount and its method, lengths of SICU and hospital stay, and mortality of study population were collected. Among 279 patients, 103 patietns (36.9%) approached target calorie intake during SICU stay. Patients who approached target calorie intake had significantly decreased length of stay in SICU (10.78 ± 11.5 vs. 15.3 ± 9.9, p = 0.001) and hospital (54.52 ± 40.6 vs. 77.72±62.2, p < 0.001), than those did not, however there was no significant difference of mortality (9.7% vs. 8.5%, p = 0.829). Enteral feeding was a significant factor for target calorie achievement (odd ratio [OR], 2.029; 95% confidence interval [CI], 1.096–3.758; p = 0.024) and especially in patients with ≤ 7 days of SICU stay (OR, 4.13; 95% CI, 1.505–11.328; p = 0.006). Target calorie achievement in surgical patients improves clinical outcomes and enteral feeding, especially in early postoperative period would be an effective route of nutrition.

Citations

Citations to this article as recorded by  
  • Energy-dense versus routine enteral nutrition in critically ill patients: a systematic review and meta-analysis
    Zonghong Zhang, Chuanlai Zhang, Huiling Pan, Ruiqi Yang, Yin Fang
    Frontiers in Nutrition.2025;[Epub]     CrossRef
  • Factors affecting target caloric achievement and calorie intake improvement: the nutrition support team's role
    Jeong Bin Bong, So-Yeong Kim, Han Uk Ryu, Hyun Goo Kang
    Frontiers in Nutrition.2024;[Epub]     CrossRef
  • 6 View
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[English]
The Lack of Association between Plant-Based Dietary Pattern and Breast Cancer: a Hospital-Based Case-Control Study
Nastaran Payandeh, Hossein Shahinfar, Mohammad Reza Amini, Alireza Jafari, Maryam Safabakhsh, Hossein Imani, Sakineh Shab-Bidar
Clin Nutr Res 2021;10(2):115-126.   Published online April 26, 2021
DOI: https://doi.org/10.7762/cnr.2021.10.2.115

Our purpose was to assess the association between plant-based dietary patterns and breast cancer (BrCa) among Iranian women. This hospital-based case-control study included 150 newly diagnosed BrCa cases and 150 age-matched controls from the Cancer Research Center, Imam Khomeini hospital, Iran. Three indices of a plant-based diet were first calculated: plant-based diet index (PDI), the healthy PDI (hPDI), and the unhealthy PDI (uPDI). In the overall PDI, all plant foods scored positively. In hPDI and uPDI, healthy and less healthy plant foods scored positive, respectively. The adjusted odds ratio (OR) in the highest adherence of PDI was 1.00 (95% confidence interval [CI], 0.55–1.83). In hPDI, 0.89 (95% CI, 0.49–1.62); in uPDI, 1.80 (95% CI, 0.95–3.42). The adjusted OR after subgroup analysis for body mass index (BMI) was as follow, BMI > 25: 0.77(95% CI, 0.37–1.61) comparing highest with the lowest tertile of PDI, 0.91(95% CI, 0.44–1.89) comparing highest with the lowest tertile of hPDI and this value for uPDI was 2.04 (95% CI, 0.91–4.56). BMI < 25: OR for top tertile of PDI was 1.82 (95% CI, 0.48–6.93), top tertile of hPDI was 1.47 (95% CI, 0.35–6.22) and top tertile of uPDI was 2.29 (95% CI, 0.54–9.70). Our results revealed no significant association between none of the PDIs and the chance of BrCa in Iranian women. Continued and expanded research, evaluated by different methods and BrCa is urgently needed to build the foundation for future progress in evidence-based public health efforts.

Citations

Citations to this article as recorded by  
  • Association Between Plant-Based Diet Index and Breast Cancer Risk Stratified by Menopausal and Hormone Receptor Status: A Case-Control Study Among Korean Women
    Jeonghee Lee, Hyeongyeong Lee, Madhawa Gunathilake, So-Youn Jung, Jeongseon Kim
    Journal of Korean Medical Science.2026;[Epub]     CrossRef
  • The association between plant-based diet indices and the risk of breast cancer: a case-control study
    Fateme Souni, Fatemeh Mansouri, Fatemeh Jafari, Reza Sharifi, Sepideh PourvatanDoust, Zainab Shateri, Mehran Nouri, Bahram Rashidkhani
    Journal of Health, Population and Nutrition.2025;[Epub]     CrossRef
  • Plant-based diet, inflammation biomarkers and body composition among women with breast cancer: the Pathways Study
    En Cheng, Chi-Chen Hong, Isaac J. Ergas, Bette J. Caan, Marilyn L. Kwan, Janise M. Roh, Ting-Yuan David Cheng, Nitika J. Sharma, Joseph R. Hanson, Hans Minderman, Haiyang Sheng, Song Yao, Neil M. Iyengar, Christine B. Ambrosone, Lawrence H. Kushi, Elizabe
    British Journal of Nutrition.2025; 133(10): 1309.     CrossRef
  • Plant-based dietary patterns and breast cancer risk in the European prospective investigation into cancer and nutrition (EPIC) study
    Sanam Shah, Nasser Laouali, Yahya Mahamat-Saleh, Carine Biessy, Geneviève Nicolas, Sabina Rinaldi, Raul Zamora-Ros, Nikos Papadimitriou, Fernanda Morales-Berstein, Christina C. Dahm, Anne Kristine Lundgård Christensen, Lene Mellemkjaer, Anne Marie Overgaa
    European Journal of Epidemiology.2025; 40(8): 947.     CrossRef
  • Associations Between Dietary Factors and Breast Cancer Risk: A Systematic Review of Evidence from the MENA Region
    Najoua Lamchabbek, Chaimaa Elattabi, Abdellatif Bour, Bernadette Chimera, Saber Boutayeb, Lahcen Belyamani, Elodie Faure, Inge Huybrechts, Mohamed Khalis
    Nutrients.2025; 17(3): 394.     CrossRef
  • Unveiling the Effects of Cruciferous Vegetable Intake on Different Cancers: A Systematic Review and Dose–Response Meta-analysis
    Sicong Zheng, Jielin Yan, Jiaxin Wang, Xinyi Wang, Yea Eun Kang, Bon Seok Koo, Yujuan Shan, Lihua Liu
    Nutrition Reviews.2025; 83(5): 842.     CrossRef
  • Pro-vegetarian dietary pattern and risk of breast cancer: a case–control study
    Yasaman Hosseini, Pegah Hadi Sichani, Elham Moslemi, Mehran Nouri, Milad Rajabzadeh-dehkordi, Saba Jalali, Zeinab Heidari, Zainab Shateri, Bahram Rashidkhani
    Breast Cancer Research and Treatment.2024; 205(2): 395.     CrossRef
  • Dietary Patterns Associated with Breast Cancer in the Middle East: A Scoping Review
    Syed Zamzam, Suad Said, Juman Yaghi, Fathima Sahar Faisal, Dana Hassan, Safa Abdul Majeed, Ala Al Rajabi, Reema Tayyem
    Nutrients.2024; 16(5): 579.     CrossRef
  • Dietary patterns and breast cancer risk, prognosis, and quality of life: A systematic review
    Yuan Bu, Junchao Qu, Siqi Ji, Jingxin Zhou, Mengxin Xue, Jiling Qu, Huiping Sun, Yongbing Liu
    Frontiers in Nutrition.2023;[Epub]     CrossRef
  • Long-term adherence to healthful and unhealthful plant-based diets and breast cancer risk overall and by hormone receptor and histologic subtypes among postmenopausal females
    Sanam Shah, Yahya Mahamat-Saleh, Wassila Ait-Hadad, Nicholas A. Koemel, Raphaëlle Varraso, Marie-Christine Boutron-Ruault, Nasser Laouali
    The American Journal of Clinical Nutrition.2023; 117(3): 467.     CrossRef
  • Scoping review of the association of plant-based diet quality with health outcomes
    Richard M. Rosenfeld, Hailey M. Juszczak, Michele A. Wong
    Frontiers in Nutrition.2023;[Epub]     CrossRef
  • Urinary Antibiotics and Dietary Determinants in Adults in Xinjiang, West China
    Lei Chu, Hexing Wang, Deqi Su, Huanwen Zhang, Bahegu Yimingniyazi, Dilihumaer Aili, Tao Luo, Zewen Zhang, Jianghong Dai, Qingwu Jiang
    Nutrients.2022; 14(22): 4748.     CrossRef
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[English]
Assessing the Effect of Zinc Supplementation on the Frequency of Migraine Attack, Duration, Severity, Lipid Profile and hs-CRP in Adult Women
Monireh Mazaheri, Arash Mosarrezaii Aghdam, Mohammad Heidari, Rasoul Zarrin
Clin Nutr Res 2021;10(2):127-139.   Published online April 27, 2021
DOI: https://doi.org/10.7762/cnr.2021.10.2.127

Migraine is a widespread incapacitating neurologic disorder with debilitating headaches which are usually throbbing due to inefficacy and several side effects, complementary therapies recommended as possible alternatives. The current randomized controlled trial was carried out to evaluate the effect of zinc gluconate supplementation on migraine-related symptoms, serum level of high sensitivity C-reactive protein (hs-CRP) and lipid profile in migraineurs. Present study was designed as randomized double-blind, placebo-controlled trial. Sixty women with migraine (mean age of 35.44 ± 7.42 years) were randomly allocated to obtain 15 mg per day of zinc gluconate or placebo for 12 weeks. Frequency, periods of headaches and severity of migraine based on numerical rating scale questionnaire and migraine disability assessment (MIDAS) test were checked. Fasting serum level of lipid profile and hs-CRP were assessed at the beginning and the end of trial. Zinc gluconate supplementation significantly reduced the frequency (p = 0.001), periods of migraine attacks (p < 0.001) and severity of migraine and MIDAS (p < 0.001) compared with control group. The serum level of low-density lipoprotein (p < 0.001), total cholesterol (p < 0.001) and hs-CRP (p < 0.001) decreased following zinc supplementation, but no significant differences in serum level of triglycerides (p = 0.1) and high-density lipoprotein (p = 0.3) was observed. However, after adjustment for baseline values using analysis of covariance test, none of lipid profile components and hs-CRP showed a significant difference. Zinc supplementation has beneficial effect on the migraine related complications like its severity, frequency.

Trial Registration

Iranian Registry of Clinical Trials Identifier: IRCT20191014045100N1

Citations

Citations to this article as recorded by  
  • Association Between Serum Zinc Level and Comorbid Orthostatic Intolerance in Pediatric Patients with Migraine
    Sachi Tokunaga, Hideki Shimomura, Naoko Taniguchi, Yasuhiro Takeshima
    Nutrients.2025; 17(23): 3753.     CrossRef
  • One-Carbon Metabolism Nutrients, Genetic Variation, and Diabetes Mellitus
    Jie Zhu, Gunjana Saikia, Xiaotao Zhang, Xiaoxi Shen, Ka Kahe
    Diabetes & Metabolism Journal.2024; 48(2): 170.     CrossRef
  • Dietary zinc intake in relation to migraine among adults: a cross sectional study of NHANES 1999–2004
    Heqing Zheng, Sheng Tian, Lanxiang Wu, Xianhui Zhong, Mingxu Liu, Xinping Yu, Yonggang Xie, Wei Wu
    Nutritional Neuroscience.2024; 27(6): 667.     CrossRef
  • Zinc Administration Favorably Affects Prophylactic Therapy-refractory Migraine Attacks: A Case Series
    Ryosuke Fukazawa, Ryotaro Ishii, Yuki Higashimoto, Misaki Hanya, Yuki Shimizu, Makiko Shinomoto, Akihiro Fujii, Toshiki Mizuno
    Internal Medicine.2024; 63(11): 1631.     CrossRef
  • The effect of selenium supplementation on oxidative stress, clinical and physiological symptoms in patients with migraine: a double-blinded randomized clinical trial
    Arghavan Balali, Omid Sadeghi, Fariborz Khorvash, Mohammad Hossein Rouhani, Gholamreza Askari
    Frontiers in Nutrition.2024;[Epub]     CrossRef
  • Heavy metal and trace element alterations in patients during a migraine attack
    Sevilay Vural, Vugar Ali Türksoy, Aytül Uzun Akgeyik, Mikail Kuşdoğan
    Headache: The Journal of Head and Face Pain.2024; 64(7): 764.     CrossRef
  • Zinc as An Emerging Therapy in the Management of Migraine: A Systematic Review
    Shubha Singhal, Sudeshna B. Dutta, Sumit Bansal, Siddhartha Dutta, Rima B. Shah
    Neurology India.2024; 72(5): 934.     CrossRef
  • Dietary zinc intake and migraine in adults: a cross‐sectional analysis of the National Health and Nutrition Examination Survey 1999–2004
    Huanxian Liu, Qi Wang, Zhao Dong, Shengyuan Yu
    Headache: The Journal of Head and Face Pain.2023; 63(1): 127.     CrossRef
  • The Role of Zinc in Modulating Acid-Sensing Ion Channel Function
    Amber W. Sun, Michelle H. Wu, Madhumathi Vijayalingam, Michael J. Wacker, Xiang-Ping Chu
    Biomolecules.2023; 13(2): 229.     CrossRef
  • Zinc supplementation and cardiovascular disease risk factors: A GRADE-assessed systematic review and dose-response meta-analysis
    Matin Nazari, Damoon Ashtary-Larky, Mahlagha Nikbaf-Shandiz, Kian Goudarzi, Reza Bagheri, Sina Dolatshahi, Hossein Salehi Omran, Niusha Amirani, Matin Ghanavati, Omid Asbaghi
    Journal of Trace Elements in Medicine and Biology.2023; 79: 127244.     CrossRef
  • Migraine and zinc deficiency in women - A mini review
    Pinky Sultana
    IP Indian Journal of Neurosciences.2022; 8(2): 93.     CrossRef
  • Effect of Evening Primrose Oil Supplementation on Biochemical Parameters and Nutrition of Patients Treated with Isotretinoin for Acne Vulgaris: A Randomized Double-Blind Trial
    Agnieszka Kaźmierska, Izabela Bolesławska, Paweł Jagielski, Adriana Polańska, Aleksandra Dańczak-Pazdrowska, Grzegorz Kosewski, Zygmunt Adamski, Juliusz Przysławski
    Nutrients.2022; 14(7): 1342.     CrossRef
  • The Role of Nutrition on Meta-inflammation: Insights and Potential Targets in Communicable and Chronic Disease Management
    Omar Ramos-Lopez, Diego Martinez-Urbistondo, Juan A. Vargas-Nuñez, J. Alfredo Martinez
    Current Obesity Reports.2022; 11(4): 305.     CrossRef
  • 11 View
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  • 13 Crossref
[English]
Genetic Variations in Thiamin Transferase SLC35F3 and the Risk of Hypertension in Koreans
Ja-young Seo, Jeong-Hwa Choi
Clin Nutr Res 2021;10(2):140-149.   Published online April 19, 2021
DOI: https://doi.org/10.7762/cnr.2021.10.2.140

Hypertension is a major health issues globally. Multiple genetic and environmental factors are involved in hypertension etiology. Solute carrier family 35 member F3 (SLC35F3) is a type of transporter uptakes thiamin across the cellular and mitochondrial membrane. Recent studies suggested that variations in SLC35F3 are associated with the risk of hypertension; however, studies are limited in Koreans. This study examined the association of the genetic variations in SLC35F3 and the risk of hypertension in Koreans using the Korean Genome Epidemiology Study (Ansan/Ansung study). A total of 8,298 Koreans (males 3,983, females 4,315) were analyzed for their general characteristics, dietary intake, and blood pressure. Twenty-four tagging variations in SLC35F3 were selected and investigated for their association with the risk of hypertension using a sex-stratified approach. Findings suggested that, in males, rs12135117 A allele carriers were at the lower risk for hypertension (adjusted odds ratio, 0.859; 95% confidence interval [CI], 0.740–0.998). In females, rs10910387 TC genotype tended to increase the risk 1.172-fold for hypertension (95% CI, 1.002–1.370). Multiple linear regression models exhibited that rs12135117 A allele was negatively associated with blood pressure in males, and rs10910387 TC genotype had a positive association with blood pressure in females. However, statistical significance for these genetically modified effects was in lacked (Bonferroni's corrected p > 0.002). In conclusion, genetic variation in SLC35F3 is not a decisive prediction marker for hypertension risk in Koreans. Given the rarity of data, more studies are required to evaluate the role of SLC35F3 and thiamin in the hypertension etiology.

Citations

Citations to this article as recorded by  
  • Modeling genotype-by-environment interactions across climatic conditions reveals environment-specific genomic regions and candidate genes underlying feed efficiency traits in tropical beef cattle
    João B. Silva Neto, Luiz F. Brito, Lucio F. M. Mota, Gustavo R. D. Rodrigues, Fernando Baldi
    Scientific Reports.2026;[Epub]     CrossRef
  • SLC35 Transporters: The Missing Link Between Glycosylation and Type 2 Diabetes
    Xu Zhang, Hafiza Mahreen Mehwish, Pulin Che
    Diabetology.2026; 7(1): 7.     CrossRef
  • RNA-seq analysis identifies key genes enhancing hoof strength to withstand barefoot racing in Standardbred trotters
    Doreen Schwochow, Asmaa Alameddine, Ellinor Spörndly-Nees, Mathilde Montigny, Rakan Naboulsi, Anna Jansson, Adnan Niazi, Gabriella Lindgren
    BMC Genomics.2025;[Epub]     CrossRef
  • Scoping review of research trends in genetic factors related to metabolic syndrome in Koreans: using the data from Korean Genome and Epidemiology Study (KoGES)
    Minyeong Kim, Subin Kim, Dayeon Shin
    Journal of Nutrition and Health.2025; 58(1): 131.     CrossRef
  • Associations of Serum Thiamine Levels with Blood Pressure Among Middle-Aged and Elderly Women in Eastern China
    Lijin Chen, Jingjing Lin, Xiangyu Chen, Zhimin Ma, Xiaofu Du, Meng Wang, Rong Chen, Jieming Zhong
    Nutrients.2025; 17(13): 2210.     CrossRef
  • The construction of a novel prognostic prediction model for glioma based on GWAS-identified prognostic-related risk loci
    Jie Wei, Yujie Li, Wenqian Zhou, Xiaoya Ma, Jie Hao, Ting Wen, Bin Li, Tianbo Jin, Mingjun Hu
    Open Medicine.2024;[Epub]     CrossRef
  • Unveiling the Enigmatic Role of SLC35F3 in Lung Adenocarcinoma
    Yiwang Ye, Feihu Long, Wei Yue, Zichun Wei, Jianyi Yang, Yuancai Xie
    The Clinical Respiratory Journal.2024;[Epub]     CrossRef
  • Solute Carrier Family 35 (SLC35)—An Overview and Recent Progress
    Shin Kamiyama, Hideyuki Sone
    Biologics.2024; 4(3): 242.     CrossRef
  • Screening and identification of key biomarkers associated with endometriosis using bioinformatics and next-generation sequencing data analysis
    Basavaraj Vastrad, Chanabasayya Vastrad
    Egyptian Journal of Medical Human Genetics.2024;[Epub]     CrossRef
  • Effects of Interaction between SLC35F3 and Carbohydrate Intake on the Incidence of Metabolic Syndrome in Korean Middle-Aged Adults
    Haeun Park, Dayeon Shin
    Nutrients.2023; 15(2): 469.     CrossRef
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  • 10 Crossref
[English]
Association of Vitamin D status with Visceral Adiposity Index and Lipid Accumulation Product Index among a Group of Iranian People
Elham Bazshahi, Sanaz Pourreza, Mahtab Ghanbari, Zeinab Khademi, Mohammad Reza Amini, Kurosh Djafarian, Sakineh Shab-Bidar
Clin Nutr Res 2021;10(2):150-160.   Published online April 26, 2021
DOI: https://doi.org/10.7762/cnr.2021.10.2.150

There is a growing body of evidence linking vitamin D and its antiadipogenic activity with body composition. The aim of this study was to investigate the association between vitamin D levels, visceral adiposity index (VAI), and lipid accumulation product index among a group of Iranian people. This cross-sectional study was conducted with 270 Iranian adults. Body composition was measured via bio-impedance analysis. The 25-hydroxyvitamin D [25(OH)D] was also measured using the enzyme-linked immunosorbent assay method. The VAI and lipid accumulation product index were calculated. Multiple linear and logistic regression after controlling for confounder was used to report the results. Multiple linear regression showed that serum 25(OH)D levels were positively correlated with age (crude: β ± standard error [SE] = 0.23 ± 0.06, p ≤ 0.001; model I: β ± SE = 0.18 ± 0.05, p = 0.002) and percent body fat (crude: β ± SE = 0.10 ± 0.04, p = 0.02). Binary logistic regression analysis showed a higher chance of greater percent body fat and lipid accumulation product index in the crude model (odds ratio [OR], 2.05; 95% confidence interval [CI], 1.13–3.72 for percent body fat and OR, 2.07; 95% CI, 1.14–3.76 for lipid accumulation product index), which disappeared after adjusting for covariates. Adults with higher vitamin D levels had higher scores of percent body fat and lipid accumulation product index. More longitudinal studies are needed to confirm these results.

Citations

Citations to this article as recorded by  
  • Association Between Serum Vitamin D Levels and Visceral Adipose Tissue in Older Adults in Iran: A Cross-Sectional Study From the Amirkola Health and Aging Project
    Marie Behnamzade, Reza Adabi, Manouchehr Ashrafpour, Reza Ghadimi, Ali Bijani, Seyed Reza Hosseini
    Clinical Nutrition Research.2025; 14(4): 308.     CrossRef
  • Association between serum vitamin D deficiency and visceral fat indices in adolescents: The Ewha Birth and growth cohort study
    Hyelim Lee, Hyunjin Park, Seunghee Jun, Hyeseung Jang, Young Sun Hong, Kyunghee Jung-Choi, Hye Ah Lee, Hyesook Park, Marwan Salih Al-Nimer
    PLOS One.2025; 20(10): e0335507.     CrossRef
  • Cholecalciferol vs. calcifediol supplementation on visceral adiposity in people with obesity: a real-world retrospective study
    Martina Chiurazzi, Mariana Di Lorenzo, Maria Serena Lonardo, Mariastella Di Lauro, Carmela Onda, Concetta Sozio, Daniela Pacella, Nunzia Cacciapuoti, Bruna Guida, Ciro Menale
    Frontiers in Nutrition.2025;[Epub]     CrossRef
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  • 3 Crossref
[English]
The Association of Dietary Phytochemical Index with Metabolic Syndrome in Adults
Fatemeh Dehghani Firouzabadi, Ahmad Jayedi, Elaheh Asgari, Mena Farazi, Zahra Noruzi, Kurosh Djafarian, Sakineh Shab-Bidar
Clin Nutr Res 2021;10(2):161-171.   Published online April 26, 2021
DOI: https://doi.org/10.7762/cnr.2021.10.2.161

In this study, we assessed the association between the dietary phytochemical index (DPI) and metabolic syndrome (MetS) among adults in a cross-sectional study. We enrolled 850 adult men and women aged 18–65 years who had been referred to health centers in Tehran, Iran. The DPI was calculated based on 8 components including fruits, vegetables, legumes, whole grains, soy products, nuts, seeds, olive, and olive oil. The odds ratio (OR) and 95% confidence interval (CI) of the MetS across quartiles of the DPI were calculated using the logistic regression analysis, adjusting for age, energy intake, marital status, education status, occupation, smoking status, physical activity, and body mass index. The mean age of participants was 44.7 ± 10.7, of whom 69% were women. The prevalence of MetS was 30.5%. The mean score of DPI in women and men was 36.2 ± 26.8 and 33.7 ± 24.7, respectively. There was no significant association between DPI and odds of MetS in men (ORfourth vs. first quartile,1.57; 95% CI, 0.64–3.84) and women (ORfourth vs. first quartile, 0.86; 95% CI, 0.50–1.49) in the fully adjusted model. There was an inverse association between DPI and increased risk of central obesity in women (ORfourth vs. first quartile, 0.54; 95% CI, 0.29–1.00; p trend = 0.03). There was no significant association between DPI and other components of the MetS in men and women. Finally, we observed no significant association between the DPI and the odds of MetS. However, the finding suggests that having a phytochemical-rich diet can be inversely associated with abdominal obesity.

Citations

Citations to this article as recorded by  
  • The Association of Phytochemical Index and oxidative balance score with bone Mineral density: a case-control study
    Marzieh Mahmoodi, Fateme Souni, Zainab Shateri, Atiyeh Sadat Hosseini, Mehran Nouri, Marzieh Ghadiri, Bahram Pourghassem Gargari
    Journal of Health, Population and Nutrition.2025;[Epub]     CrossRef
  • Bioactive Compounds Derived From Natural Foods Against Metabolic Syndrome and the Advances of Resveratrol and Caffeic Acid in Microbial Cell Factory Production: A Review
    Tao Li, Jingjing Shi, Tao Liu, Chongxiang Xue, Lin Han, Mingzhe Zhang, Linhua Zhao, Xiaolin Tong
    Food Frontiers.2025; 6(6): 2575.     CrossRef
  • The Dietary Phytochemical Index Is Inversely Associated With the Odds of Premature Coronary Artery Disease (PCAD) in Iranian Adults: Iran Premature Coronary Artery Disease (IPAD) Study
    Motahare Bateni, Ehsan Zarepur, Fahimeh Haghighatdoost, Noushin Mohammadifard, Minoo Dianatkhah, Alireza Khosravi Farsani, Nahid Azdaki, Nahid Salehi, Masoud Lotfizadeh, Samad Ghaffari, Arsalan Salari, Mostafa Cheraghi, Ahmadreza Assareh, Mehrnoosh Arefia
    Food Science & Nutrition.2025;[Epub]     CrossRef
  • Dietary Phytochemical Index and Risk of Gallstone Disease: A Case‐Control Study
    Zeinab Ghaeminejad, Leyli Zahra Bahreini Boroujeni, Fatemeh Javaheri‐Tafti, Seyed Ali Abbas‐Hashemi, Azita Hekmatdoost, Moloud Ghorbani, Amir Sadeghi, Zahra Yari
    Health Science Reports.2025;[Epub]     CrossRef
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Case Report
[English]
Nutrition Intervention Process for Heart Failure Patients according to Their Nutritional Problems
Hosun Lee, Suk Yong Jeong, Hae Ryeon Choi, Seok-Min Kang
Clin Nutr Res 2021;10(2):172-180.   Published online April 23, 2021
DOI: https://doi.org/10.7762/cnr.2021.10.2.172

Patients with heart failure (HF) need nutritional management such as sodium restriction and healthy eating habits to relieve symptoms and to manage chronic disease. This case study examined 3 patients who had different nutritional problems and responded positively to the nutrition management program. Patient 1 and 2 had high levels of energy intake and were obese. Patient 1 had a habit of irregular binge eating and frequently consumed sweetened snacks and fast foods. He was advised to eat regular 3 meals per day with balanced food choices. He decreased his energy consumption to the recommenced intake and his body mass index had dropped to 22.9 kg/m2 by his second follow-up visit. Patients 2 ate 3 meals regularly but ate a large amount of food. Although he decreased his energy intake to 97% of the recommended intake, he should be advised to increase his protein intake at the 1st follow-up session because he decreased his protein intake less than 90% of the recommended amount. Patient 3 reduced food intake by half due to dyspnea caused by HF before hospitalization, but symptoms improved after discharge and his energy as well as sodium intake increased. In the second follow-up, his nutritional diagnosis was excessive sodium intake and nutritional intervention was performed to reduce sodium intake. This study showed that additional nutritional problems might arise throughout the nutritional intervention process. Therefore, follow-up nutritional counseling should be held to evaluate the compliance with the nutrition management guidelines and to decide whether additional nutrition problems are suggested.

Citations

Citations to this article as recorded by  
  • The heart–brain axis: neurocognitive frailty in heart failure
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  • The Nutritional Status of Patients with Heart Failure and Its Impact on Patient’ Outcomes—The Center’s Own Experience
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  • Prognostic value of nutritional screening tools in hospitalized patients with decompensated heart failure: A systematic review and meta-analysis
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