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Original Article

Effects of Chromium Picolinate Supplementation on Cardiometabolic Biomarkers in Patients with Type 2 Diabetes Mellitus: a Randomized Clinical Trial

Aria Tavakoli Talab1orcid, Hadi Abdollahzad2orcid, Seyyed Mustafa Nachvak2orcid, Yahya Pasdar2orcid, Shahryar Eghtesadi3orcid, Azimeh Izadi4orcid, Mir Amir Aghdashi5orcid, Mohammad Reza Mohammad Hossseini Azar5orcid, Sedighe Moradi6orcid, Behzad Mehaki7orcid, Shima Moradi2orcid
Clinical Nutrition Research 2020;9(2):97-106.
Published online: April 24, 2020

1Be'sat Hospital, Hamadan University of Medical Sciences, Hamadan 6517838678, Iran.

2Department of Nutrition, Research Center for Environmental Determinants of Health, Health Institute, Kermanshah University of Medical Sciences, Kermanshah 6719851351, Iran.

3Islamic Azad University; Tehran Medical Branch and Science & Research Branch, Tehran 1477983855, Iran.

4Students' Research Committee, Faculty of Nutrition, Tabriz University of Medical Sciences, Tabriz 5166614711, Iran.

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Correspondence to Hadi Abdollahzad. Department of Nutrition, Research Center for Environmental Determinants of Health, Health Institute, Kermanshah University of Medical Sciences, Kermanshah 6719851351, Iran. hadi_nut@yahoo.com; abdollahzad@kums.ac.ir
• Received: February 5, 2020   • Revised: April 17, 2020   • Accepted: April 19, 2020

Copyright © 2020. The Korean Society of Clinical Nutrition

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effects of Chromium Picolinate Supplementation on Cardiometabolic Biomarkers in Patients with Type 2 Diabetes Mellitus: a Randomized Clinical Trial
Clin Nutr Res. 2020;9(2):97-106.   Published online April 24, 2020
DOI: https://doi.org/10.7762/cnr.2020.9.2.97
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Effects of Chromium Picolinate Supplementation on Cardiometabolic Biomarkers in Patients with Type 2 Diabetes Mellitus: a Randomized Clinical Trial
Clin Nutr Res. 2020;9(2):97-106.   Published online April 24, 2020
DOI: https://doi.org/10.7762/cnr.2020.9.2.97
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Effects of Chromium Picolinate Supplementation on Cardiometabolic Biomarkers in Patients with Type 2 Diabetes Mellitus: a Randomized Clinical Trial
Image
Figure 1 CONSORT flowchart of study.

Figure 1

Effects of Chromium Picolinate Supplementation on Cardiometabolic Biomarkers in Patients with Type 2 Diabetes Mellitus: a Randomized Clinical Trial
Table 1 Baseline characteristics of patients with type 2 diabetes mellitus

Data are presented as number (percent) for sex and mean ± standard deviation for other variables. Data were analyzed using Fisher exact test for sex and Independent t-test for other variables.

NS, not significant; BMI, body mass index.

Table 2 Dietary intakes of patients with type 2 diabetes mellitus

Data are presented as mean ± standard deviation.

NS, not significant; SFA, saturated fatty acid; MUFA, monounsaturated fatty acid; PUFA, polyunsaturated fatty acid.

Between groups comparisons of *baseline and †endpoint using independent t-test except indicated with ‡which analyzed by Mann-Whitney test.

Table 3 Metabolic biomarkers of patients with type 2 diabetes mellitus before and after the intervention

Data are presented as mean ± standard deviation.

NS, not significant; LDL-C, low-density lipoprotein; HDL-C, high-density lipoprotein; FBG, fasting blood glucose; HOMA-IR, homeostatic model assessment for insulin resistance.

*Within groups' analysis by paired t-test except indicated with which analyzed by Wilcoxon test. †Between groups' comparisons at baseline by independent t-test except indicated with which analyzed by Mann-Whitney test. ‡ANCOVA for between groups analysis after adjustment of dietary intakes and baseline levels of each variable, §independent t-test for between groups' changes analyses.

Table 1

Table 2

Table 3

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