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Case Report

[English]
This case report showed the gradual progression and compliance of EEN in a critically ill patient with septic shock requiring vasopressors, and the progression observed was relatively in line with existing studies and guidelines.
Enteral Nutrition in Critically Ill Patient With Septic Shock Requiring Vasopressor: Case Report
Hee Young Kim, Min Young Noh, Jisun Lee
Clin Nutr Res 2024;13(1):1-7.   Published online January 26, 2024
DOI: https://doi.org/10.7762/cnr.2024.13.1.1

Nutritional support in critically ill patients is an essential aspect of treatment. In particular, the benefits of enteral nutrition (EN) are well recognized, and various guidelines recommend early EN within 48 hours in critically ill patients. However, there is still controversy regarding EN in critically ill patients with septic shock requiring vasopressors. Therefore, this case report aims to provide basic data for the safe and effective nutritional support in septic shock patients who require vasopressors. A 62-year-old male patient was admitted to the intensive care unit with a deep neck infection and mediastinitis that progressed to a septic condition. Mechanical ventilation was initiated after intubation due to progression of respiratory acidosis and deterioration of mental status, and severe hypotension required the initiation of norepinephrine. Due to hemodynamic instability, the patient was kept nil per os. Subsequently, trophic feeding was initiated at the time of norepinephrine dose tapering and was gradually increased to achieve 75% of the energy requirement through EN by the 7th day of enteral feeding initiation. Although there were signs of feeding intolerance during the increasing phase of EN, adjusting the rate of EN resolved the issue. This case report demonstrates the gradual progression and adherence to EN in septic shock patient requiring vasopressors, and the progression observed was relatively consistent with existing studies and guidelines. In the future, further case reports and continuous research will be deemed necessary for safe and effective nutritional support in critically ill patients with septic shock requiring vasopressors.

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Original Articles

[English]
This study provided multidisciplinary education, including nutrition, exercise, and psychological education, and observed significant improvements in nutrition-related factors after the education program.
Effects of Multidisciplinary Health Promotion Program Among Children in Community Childcare Center
Yerin Kim, Gyeong Seob Shin, Jungwon Park, Minji Kang, Kumhee Son, Yoon Myung Kim, Kyung Hee Park, Hyunjung Lim
Clin Nutr Res 2024;13(1):8-21.   Published online January 23, 2024
DOI: https://doi.org/10.7762/cnr.2024.13.1.8

In this study, the effects of a 12-month multidisciplinary education program on the health status, dietary quality, and eating habits of children and adolescents attending community childcare centers were investigated. A total of 88 participants aged 7 to 17 years from 7 community childcare centers in Gyeonggi-do were enrolled. The intervention consisted of 12 multidisciplinary education sessions covering topics such as nutrition, exercise, and psychological education. All participants received the same education, and the effectiveness of the program was evaluated by categorizing them into a high participation group (HPG) and a low participation group (LPG) based on their participation rates. After intervention, in physical activities, moderate-intensity exercise was significantly reduced in the LPG, and there was no significant difference in psychological parameters. However, notable differences were observed in nutritional data. After intervention, intakes of calorie, carbohydrate, protein, and fat were significantly increased in both groups, and in particular, the change was found to be greater in HPG. Additionally, dietary fiber intake compared to the 2015 Korean Dietary Reference Intakes was increased in both groups. Daily food intake also increased dietary fiber intake in HPG, and meat and fruit intake was increased in LPG. In the nutrition quotient, there was a significant difference in HPG’s pre- and post-scores in the diversity category, and in nutrient adequacy ratio (NAR), the NAR of phosphorus was increased in both groups. The findings of this study suggest that multidisciplinary education implemented at community childcare centers primarily enhanced nutrition-related factors rather than physical activity or psychological aspects.

Trial Registration

Clinical Research Information Service Identifier: KCT0002718

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[English]
Dietary fiber intake was associated with low muscle strength in older Korean women aged ≥ 65 years.
Association Between Dietary Fiber Intake and Low Muscle Strength Among Korean Adults
Sunhye Shin
Clin Nutr Res 2024;13(1):33-41.   Published online January 31, 2024
DOI: https://doi.org/10.7762/cnr.2024.13.1.33

The health benefits of dietary fiber are widely recognized, but its impact on muscle health remains unclear. Therefore, this study aimed to elucidate the relationship between dietary fiber intake and muscle strength through a cross-sectional analysis of data from the Korea National Health and Examination Survey (KNHANES). Data from a single 24-h dietary recall and handgrip strength tests of 10,883 younger adults aged 19 to 64 years and 3,961 older adults aged ≥ 65 years were analyzed. Low muscle strength was defined as handgrip strength < 28 kg for men and < 18 kg for women. Multivariable linear and logistic regression analyses were conducted to determine the association of dietary fiber intake with muscle strength. Approximately 43% of Korean adults met the recommended intake of dietary fiber, and those with higher dietary fiber consumption also had higher total energy and protein intake. After adjusting for confounding variables, dietary fiber intake was found to be positively associated with maximal handgrip strength in younger women aged 19 to 64 years (β = 0.015; standard error [SE] = 0.006) and older men aged ≥ 65 years (β = 0.035; SE = 0.014). For older women aged ≥ 65 years, those in the lowest quartile of dietary fiber intake had a higher risk of low muscle strength than those in the highest quartile after adjustment of confounders (odds ratio 1.709; 95% confidence interval 1.130–2.585). These results suggest that adequate dietary fiber intake may reduce the risk of sarcopenia in older Korean women.

Citations

Citations to this article as recorded by  
  • Beneficial effects of Tteokbokki sauce meeting the functional labeling system claim on dexamethasone-induced C2C12 myotube and hindlimb immobilization-induced C57BL/6J mice
    Geon Oh, Xionggao Han, Xiao Men, Ji-Hyun Im, Xiaolu Fu, June-Seok Lim, Luri Lee, Min Hee Kwon, Ho-Seong Lee, Moon Jin Ra, Sun-Il Choi, Ok-Hwan Lee
    Food Science and Biotechnology.2025; 34(3): 757.     CrossRef
  • The association between eight dietary factors and sarcopenia: evidence from NHANES data
    Xingfu Fan, Yang Luo, Xiaofang Li, Wenqin Tan, Shiping Liu, Jin Zhao
    Journal of Health, Population and Nutrition.2025;[Epub]     CrossRef
  • Sarcopenic obesity in the Asia-Pacific region: Epidemiology, risk factors, and management
    Chun-Feng Huang, Chih-Hsing Wu
    Osteoporosis and Sarcopenia.2025; 11(2): 40.     CrossRef
  • Advanced Understanding of Dietary Fiber With Omics
    Sumin Park, Jiwoo Park, Yang Sueun Lee, Nakyoung Shin, Mihi Yang
    Food Supplements and Biomaterials for Health.2025;[Epub]     CrossRef
  • Temporal Trends in Handgrip Strength and Associated Factors among Korean Adults from 2014 to 2019: Analysis of Korea National Health and Nutrition Examination Survey Data
    Yun Ki Kim, Sukyoung Jung, Seung Hoo Lee, Jaehee Seo
    Clinics in Orthopedic Surgery.2025; 17(5): 891.     CrossRef
  • Time-Restricted Eating and Prebiotic Supplementation Demonstrate Feasibility and Acceptability in Young Adult Pediatric Cancer Survivors: A Randomized Controlled Pilot Trial
    Kate Cares, Manoela Lima Oliveira, Alyssa Bryner, Bernice Man, Zhengjia Chen, Beatriz Peñalver Bernabé, Mary Lou Schmidt, Marian Fitzgibbon, Kelsey Gabel
    Nutrients.2025; 17(20): 3306.     CrossRef
  • Association Between Serum High Sensitivity C-Reactive Protein Levels and Low Muscle Strength Among Korean Adults
    Bo-Hyun Choi, Sunhye Shin
    Nutrients.2025; 17(16): 2698.     CrossRef
  • Low dietary vitamin C intake is associated with low muscle strength among elderly Korean women
    Chan Yoon Park, Sunhye Shin
    Nutrition Research.2024; 127: 75.     CrossRef
  • Plant-Based Diets and Their Associations with Physical Performance in the Baltimore Longitudinal Study of Aging
    Galya Bigman, Marius Emil Rusu, Amber S. Kleckner, John D. Sorkin, Yichen Jin, Sameera A. Talegawkar, Toshiko Tanaka, Luigi Ferrucci, Alice S. Ryan
    Nutrients.2024; 16(23): 4249.     CrossRef
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[English]
Disintegration times of Tylenol tablets immersed in thickened beverages at different thickness levels or the swallowing aid jelly products.
Effect of Thickened Beverage and Swallowing Aid Jelly Used for Dysphagic Patients on the Disintegration of Orally Administered Tablets
Won Hyeong Cho, Whachun Yoo, Byoungseung Yoo
Clin Nutr Res 2024;13(2):89-95.   Published online April 25, 2024
DOI: https://doi.org/10.7762/cnr.2024.13.2.89

Thickened beverages or swallowing aid jelly (SAJ), commonly used as tablet-swallowing aids for dysphagic patients, may influence the disintegration of orally administered tablets. With this in mind, we evaluated the disintegration times of therapeutic tablets immersed in thickened beverages or SAJ compared to immersion in ones without them. Thickened beverages and SAJs were prepared with various beverages (water, orange juice, and milk) using food thickeners and SAJ powders marketed in Korea. The tablet disintegration times were the same in thickened beverages and SAJs, and there was no statistically significant difference associated with the thickness levels of the thickened beverages. The disintegration times of Tylenol immersed in orange juice or milk were slightly higher compared to those immersed in water. Moreover, there was no difference in disintegration time when using the thickened beverages and SAJs. The disintegration times of Aspirin were similar in all of the thickened beverages or SAJs, and there were no differences between non-immersed and immersed tablets. These results demonstrate that the disintegration of Tylenol and Aspirin is not greatly affected by immersion in any of the thickened beverages and SAJs.

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[English]
It was found that most elderly care facilities in Korea provide fruit to the elderly only 1~3 times a week, suggesting that efforts should be made to expand the supply of snacks in appropriate quantities and varieties to improve the quality of life of the elderly and increase the efficacy of fruits.
Snack Provision Practice in Long-Term Care Hospitals and Facilities in Korea
Dayeong Yeo, Hae Jin Kang, Hyejin Ahn, Yoo Kyoung Park
Clin Nutr Res 2024;13(2):108-120.   Published online April 30, 2024
DOI: https://doi.org/10.7762/cnr.2024.13.2.108

The study aimed to investigate the basic data to derive plans for snack provision to improve the nutritional status of older adults living in long-term care facilities (LFs) or long-term care hospitals (LHs). The 252 respondents (118 from LHs and 134 from LFs) were included in the study. The questionnaire of nationwide cross-sectional survey was developed by the authors and registered dietitians. The written questionnaire was sent to the food service managers across 800 LFs or LHs. The online survey was introduced using the online platform and network site for dietitians. More than 70% of live-in and non-live-in LFs provided snacks, which were mainly provided one to two times a day. Most institutions provided fruits one to three times a week. The main considerations when providing fruit were in the order of residents’ preference, cost, and ease of consumption. The reasons for not serving fruit included cost and differences in the residents’ eating and mastication abilities. Most institutions also provided dairy products at a frequency of one to three times a week. The reasons for not serving dairy products included cost and the lack of awareness of the need to provide them. To improve the quality of life and the offer benefits of fruits and dairy products to older people, efforts are needed to propose a plan to expand the provision of snacks in appropriate quantities and varieties.

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Case Report

[English]
Periodic assessments and consultations with a Nutrition Support Team are recommended to monitor the patient's growth and nutritional status.
Nutritional Intensive Support in a Pediatric Patient With Severe Traumatic Brain Injury: A Case Report
In Seok Lee, Kyounglan Kang, Yun Mi Chung, Junghwa Lee
Clin Nutr Res 2024;13(3):149-155.   Published online July 25, 2024
DOI: https://doi.org/10.7762/cnr.2024.13.3.149

Estimating the nutritional requirements for pediatric patients requires a comprehensive approach with various factors including age, gender, body mass index, and physical activity level, due to the significant growth and developmental changes observed in this population. This complexity renders the use of a simplistic generalization or a standard formula impractical. A number of methodologies have been established to calculate nutritional needs for the pediatric population. However, the application of these methodologies is challenging due to the variability in the aforementioned factors. Determining nutritional requirements for pediatric patients with underlying medical conditions is complicate, influenced by variables such as the nature of the illness, treatment modalities, and the patient’s overall condition. Nutritional support in severely traumatically brain-injured pediatric patients is directly correlated with prognosis and growth outcomes. Therefore, this case study aims to validate existing methodologies for estimating nutritional requirements in pediatric patients with severe traumatic brain injury and to provide primary data for the development of effective nutritional support strategies. A case of a 5-year-old male patient admitted to the intensive care unit due to severe traumatic brain injury is examined. Future case studies and ongoing research are imperative to ensure the safe and effective nutritional support of pediatric patients with severe traumatic brain injury.

Citations

Citations to this article as recorded by  
  • Implementation of bioimpedance body composition analysis in the comprehensive assessment of nutritional status of children after severe traumatic brain injury
    A. A. Akhmadullina, R. F. Rakhmaeva, E. M. Akhmadullina, A. A. Kamalova
    Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics).2025; 70(5): 29.     CrossRef
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Original Article

[English]
The energy content was significantly higher in cooked rice, but the protein content and INQ were significantly greater in mousse, suggesting that cooked rice is appropriate as a staple senior-friendly food in terms of energy supply, but mousse can be an alternative for protein supplementation for people with dietary restrictions.
Nutritional Assessment of Protein and Sodium Contents in Commercial Senior-Friendly Foods
Yun-A Lee, Mi-Kyeong Choi
Clin Nutr Res 2024;13(3):156-164.   Published online July 25, 2024
DOI: https://doi.org/10.7762/cnr.2024.13.3.156

The purpose of this study was to evaluate the nutritional adequacy of senior-friendly foods sold in Korea, focusing on protein and sodium. This study examined the nutritional content of 170 products with nutritional labels that were sold in online stores in Korea and categorized the products into 93 staple foods (cooked rice, porridge, and mousse) and 77 side-dish and snack foods (braized·steam·roast products, broth, sauces, and snacks). Then, the adequacy of the nutritional content of these foods, focusing on protein and sodium, was evaluated according to product type. The 93 staple products and 77 side-dish products had average serving sizes of 163.27 g and 127.92 g, prices of $3.25 and $2.72, and energy contents of 295.25 kcal and 141.95 kcal, respectively. For staple foods, the energy content was significantly greater in cooked rice, but the protein content and index of nutrition quality (INQ) were significantly greater in mousse. There were no significant differences in sodium content or contribution to adequate intake (AI) by product type, but the sodium INQ was significantly greater in the mousse and porridge. For side-dish foods and snack products, the protein content, contribution to the recommended intake, and INQ were all significantly greater for the braized·steam·roast products. Sauces and braized·steam·roast products were significantly higher in sodium content and contribution to the AI, while broth was significantly higher in sodium INQ. These findings can be used to guide proper product selection and nutritional management that considers the health characteristics of health-vulnerable and elderly people.

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Review Article

[English]
Herbal tea supplementation among women with PCOS significantly decreased body weight, BMI, and serum FBG concentrations and increased FSH levels in the intervention group compared to the control.
Association of Herbal Tea and Follicle-Stimulating Hormone, Anthropometric Parameters, and Fasting Blood Glucose Levels Among Polycystic Ovarian Syndrome Women: A Systematic Review and Meta-Analysis of Clinical Trials
Elahe Abbasi, Zahra Hajhashemy, Gholamreza Askari, Parvane Saneei
Clin Nutr Res 2024;13(3):201-213.   Published online July 30, 2024
DOI: https://doi.org/10.7762/cnr.2024.13.3.201

This systematic review and meta-analysis of randomized controlled trials (RCTs) aimed to test our hypothesis that herbal tea may improve anthropometric parameters, metabolic factors, and hormone levels in women with polycystic ovarian syndrome (PCOS). A literature search was conducted on Information Sciences Institute, Medline (PubMed), Scopus, Embase, and Google Scholar, up to March 2023 without applying language or date restrictions. RCTs that assigned herbal tea vs. placebo on PCOS women and evaluated changes in anthropometric measurements, metabolic indices, or hormonal profiles were included. Six RCTs with 235 PCOS women (119 in the intervention and 116 in the control group) were included. Meta-analysis showed that herbal tea consumption led to significant decreases in weight (weighted mean difference [WMD], −2.02 kg; 95% confidence interval [CI], −3.25, −0.80), body mass index (BMI) (WMD, −0.88 kg/m2; 95% CI, −1.47, −0.28) and fasting blood glucose (FBG) (WMD, −6.47 mg/dL; 95% CI, −8.49, −4.45), compared to the control group. Herbal tea supplementation has also significantly increased follicle-stimulating hormone (FSH) concentration (WMD, 0.56 IU/L; 95% CI, 0.17, 0.95). Meanwhile, the effect of herbal tea on the waist/hip ratio, hip circumference, waist circumference, body fat, fasting insulin, FBG/insulin ratio, luteinizing hormone, total testosterone, and dehydroepiandrosterone sulfate was not significant. Herbal tea might be a potential supplemental therapy to manage weight, BMI, FBG, and FSH in PCOS women. Further large randomized clinical trials are recommended to affirm these findings.

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Special Report

[English]
2023 Korean Food Exchange Lists : Energy and macronutrient contents per exchange unit for each food group.
Korean Food Exchange Lists for Diabetes Meal Planning: Revised 2023
Jae Won Cho, Dal Lae Ju, YeonHee Lee, Bo Kyung Min, Meera Kweon, Eun Mi Kim, SuJin Song, Jae Eun Shim, Oh Yoen Kim, Suk Chon, Jeong Hyun Lim
Clin Nutr Res 2024;13(4):227-237.   Published online October 29, 2024
DOI: https://doi.org/10.7762/cnr.2024.13.4.227

A food exchange list is a tool developed to help diabetic patients control their energy intake and plan balanced meals. Korean food exchange lists were first developed in 1988, revised in 1995, and updated again in 2010. With rapidly changing dietary habits and increasing demand for diverse food cultures, the Korean Diabetes Association in cooperation with 4 related organizations established a Task Force Team (TFT) to revise food exchange lists in March 2022. Starting with a workshop, TFT held 11 official revision meetings, culminating in a public hearing in May 2023. The final revised version of Korean food exchange lists was published in December 2023. Key outcomes of the revision are summarized as follows: 1. Based on the National Standard Food Composition Table 10.0 database, the existing classification system and nutrient standards for each food group remain unchanged this time. 2. Based on a survey conducted among diabetes educators, the number of items on the food exchange lists has increased from 339 in 2010 to 435 this time. 3. Considering patients’ usual eating habits, meal planning examples were developed distributing food group exchange units by energy level based on 3 types of proportions of carbohydrate energy (40%–45%, 50%–55%, 60%–65%). 4. Due to limitations in real-time updates for rapidly changing information, detailed guidance on how to access and interpret the data is provided. These revisions will help people with diabetes manage their blood sugar levels and facilitate the implementation of healthy meal planning in various other conditions, including obesity.

Citations

Citations to this article as recorded by  
  • Development of Nutritional Counseling Materials for ASD Children: Focusing on the Food Exchange List
    Seunghyun Won, Youjeong Kim, Jiye Park, Su-In Yoon, Jin Ah Cho
    Clinical Nutrition Research.2025; 14(2): 127.     CrossRef
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Original Articles
[English]
Adolescent athletes who participated in the 12-week intensive nutrition intervention in the 5A’s behavioral change model increased nutritional knowledge and nutrient intake.
5A's Behavior Change Model Improves Nutrition Knowledge and Intake Among Adolescent Athletes
Saningun Lee, Yeongtaek Hwang, Hyunjung Lim
Clin Nutr Res 2024;13(4):244-256.   Published online October 29, 2024
DOI: https://doi.org/10.7762/cnr.2024.13.4.244

This study compared the effects of 12 weeks of intensive nutrition education (IE) using the 5A's behavioral change model and basic nutrition education (BE) on nutritional knowledge and nutrient intake among Korean adolescent athletes. This study included elite adolescent athletes (IE group: n = 65, BE group: n = 65) at a physical education high school in Seoul. In this prospective, randomized, controlled trial, the athletes' body composition, nutritional knowledge, nutrient intake, and self-management practices were evaluated at the beginning and end of the intervention. Both groups had increased levels of nutrition knowledge between pre- and post-test, but the change in total score for nutrition knowledge was significantly higher in the IE group than in the BE group (p < 0.001). Energy intake post-test increased significantly in the IE group (from 2,185 to 2,651 kcal/day, p < 0.001) but not in the BE group. The intake of carbohydrates, protein, and fat also increased significantly in the IE group (carbohydrates: from 298 to 352 g/day, protein: from 86 to 106 g/day, fat: from 71 to 88 g/day, all p < 0.001), but the change in the BE group was not significant. Additionally, the IE group showed a significant overall increase in vitamins and minerals compared to the BE group at post-test. Adolescent athletes in the IE group showed improved nutritional knowledge and intake compared to those in the BE group 12 weeks after the intervention.

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[English]
Nutrition experts and policy-makers need to increase efforts to maintain interest in NFLs that emerged during the pandemic.
Continuous Postpandemic Increase in the Use of Nutrition Fact Labels Among Korean Adults: A Weighted Multiyear Analysis of a Nationwide Survey
Jung Min Cho
Clin Nutr Res 2024;13(4):257-271.   Published online October 29, 2024
DOI: https://doi.org/10.7762/cnr.2024.13.4.257

Nutrition fact labels (NFLs) have advantages because they are an intuitive tool that provides unified information regulated by the government and does not require any devices or special skills. During pandemic, with increased interest in information about healthy food choices and optimum nutrition, frequent exposure to NFLs on pre-packaged foods and dietary supplements may have helped consumers become aware of and/or use NFLs. We aimed to evaluate NFL usage changes from the pre- and early to the late pandemic years in the Korean adult population, using data from the Korean Community Health Survey (3-year total respondents n = 687,610) conducted from 2019 to 2021. NFL awareness, effect, and utilization ratios in each subgroup (sex, age, diabetes mellitus/hypertension, subjective health status, and physical activity) were analyzed for the 3 years by the cross-tabulation test of weighted complex sample analysis. Despite the declining awareness of NFLs in the Korean population, the proportion of individuals who were affected by the NFL content in the entire population and the utilization ratio among those who were aware of NFLs increased continuously during the early and late pandemic periods. Thus, Nutrition experts and policy-makers need to increase efforts to maintain interest in NFLs that emerged during the pandemic. NFLs, a conventional but well-regulated and effective tool, may have enabled the Korean population to make healthy food choices during the pandemic.

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